Painkillers were linked to an increased heart attack risk, according to a study published in the British Medical Journal. As stated in the meta-analysis, which was led by epidemiologist Michèle Bally, patients who were prescribed larger doses oral non-steroidal anti-inflammatory drugs were more likely to suffer from acute myocardial infarction within 30 days of first taking the drugs.
For their meta-analysis, the researchers examined the medical records of 446,763 patients – which were obtained from Canadian and European medical and prescription databases.
The study specifically examined the use of NSAIDs, including diclofenac, celecoxib, ibuprofen, naproxen, and rofecoxib — which are commonly prescribed to treat fever, inflammation, and pain. Although NSAIDs are available over the counter, higher doses generally require a prescription.
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