How, exactly, does exercise keep you thin? Researchers at the University of Florida have a pretty good idea. They have learned that Irisin, a hormone that surges when muscles are exerted, somehow tells the body to shed fat and hinders it from making more fat. A University of Florida news release reports that the researchers collected fat cells from 28 patients who had breast reduction surgery. After exposing the samples to irisin, they found a nearly fivefold increase in cells that contain a protein known as UCP1 that is crucial to fat “burning.” The researchers also found that irisin suppresses fat-cell formation. Among the tested fat-tissue samples, irisin reduced the number of mature fat cells by 20 to 60 percent compared with those of a control group, a finding that suggests that irisin reduces fat storage in the body by hindering the process that turns undifferentiated stem cells into fat cells while also promoting the stem cells’ differentiation into bone-forming cells.
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